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notopterol (5
InChi: InChI=1S/C43H67N11O12S2/c1-5-23(3)35-41(63)53-36(24(4)55)42(64)50-29(20-32(45)56)38(60)51-30(43(65)54-17-8-10-31(54)40(62)49-27(9-7-16-44)37(59)47-21-33(46)57)22-68-67-18-15-34(58)48-28(39(61)52-35)19-25-11-13-26(14-12-25)66-6-2/h11-14
Athyala PK
InChiKey: AHJRHEGDXFFMBM-UHFFFAOYSA-N
when added to human plasma
CC-223 15789 notopterol (5CC 223 is a potent, selective, and orally bioavailable inhibitor of mTOR kinase, with an IC50 value for mTOR kinase of 16 nM. CC 223 inhibits both mTORC1 and mTORC2. Product information CAS Number: 1228013 30 6 Molecular Weight: 397. 47 Formula: C21H27N5O3 Chemical Name: 7 [6 (2 hydroxypropan 2 yl)pyridin 3 yl] 1 [(1r,4r) 4 methoxycyclohexyl] 1H,2H,3H,4H pyrazino[2,3 b][1,4]diazin 2 one Smiles:
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